A recent review article investigated the importance of hyaluronic acid chain lengths in eye drops for the physical as well as physiological performance of the drops. The classification according to average molecular weight was proposed: LMW HA (low molecular weight hyaluronic acid: < 1.5 MDa), MMW HA (medium molecular weight hyaluronic acid: 1.5 – 2.3 … Continue reading Hylan A supports the growth of corneal nerves in patients suffering from severe dry eye disease
Tag: dry eye
Tearfilm oriented dry eye therapy
In 2017 the Tear Film and Ocular Surface Society (TFOS) published the results of the second Dry Eye Workshop (DEWS II) in a number of consensus papers on the definition, diagnosis, pathophysiology and treatment of dry eyes. DEWS II defined dry eye as “a multifactorial disease of the ocular surface characterized by a loss of homeostasis … Continue reading Tearfilm oriented dry eye therapy
Corneal nerves in health and disease
The corneal surface is the body’s most densely innervated tissue. Nevertheless, until recently the ocular innervation has not taken too much attention, because most sight-threatening diseases like glaucoma, cataract or retinal pathologies occur and progress without pain. The Tear Film and Ocular Surface Socienty (TFOS) has established a working group on ocular surface pain and … Continue reading Corneal nerves in health and disease
Homeostasis of the Ocular Surface
Big Pharma prefers medicines with a defined mode of action (MoA). It eases regulatory approval, reimbursement by public insurance, marketing, and communication with the physicians. Side effects are accepted as collateral damages. Studies for the approval of new topical eye drops frequently compare the new drug with its vehicle (i.e. the drug formulation without the … Continue reading Homeostasis of the Ocular Surface
Dr. Mueller-Lierheim 