Why chain length of hyaluronan in eye drops matters

The chain length of hyaluronan (HA) determines its physical as well as its physiological properties. Results of clinical research on HA eye drops are not comparable without this parameter. In a recent article methods for the assessment of the average molecular weight of HA in eye drops and a terminology for molecular weight ranges are … Continue reading Why chain length of hyaluronan in eye drops matters

Wholism in Medicine – My Meetings with Dr. Wei-Kung Wang

Wholism (holism) is the idea that different parts are interconnected and cannot be understood without understanding the whole.  In 1998 a Taiwanese friend from ITRI (the Industrial Technology Research Institute in Hsinchu) introduced me to Professor Wei-Kung Wang, a research fellow with the Biophysics Laboratory, Institute of Physics, Academia Sinica in Taipei, who had received … Continue reading Wholism in Medicine – My Meetings with Dr. Wei-Kung Wang

Homeostasis of the Ocular Surface

Big Pharma prefers medicines with a defined mode of action (MoA). It eases regulatory approval, reimbursement by public insurance, marketing, and communication with the physicians. Side effects are accepted as collateral damages. Studies for the approval of new topical eye drops frequently compare the new drug with its vehicle (i.e. the drug formulation without the … Continue reading Homeostasis of the Ocular Surface